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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 12.73
Human Site: S497 Identified Species: 25.45
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 S497 P S R P H P G S L P F S T A P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 L479 A N R H P A G L T F P T A P G
Dog Lupus familis XP_536720 1330 145448 S572 P S R P H P G S L P F S A A P
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 S498 P S R P H P G S L P F S A A P
Rat Rattus norvegicus XP_002726668 1257 138805 S498 P S R P H P G S L P F S A A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 V254 M Q G P R E G V A G E S K R H
Chicken Gallus gallus XP_417551 908 100815 Y183 H V N D Q I Y Y K V I K E I E
Frog Xenopus laevis B7ZRU9 1055 118966 G330 S P V K G L P G V E Q S S K S
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 E428 S L S S Q S E E N R E S K L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 L265 L R F C H R P L L I K H E A I
Honey Bee Apis mellifera XP_001121599 1541 171480 F538 M G P Y P G I F P N A P N F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 K977 S T V T S L N K H R R F C H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 13.3 93.3 N.A. 93.3 93.3 N.A. 20 0 6.6 6.6 N.A. 20 0 N.A. 0
P-Site Similarity: 100 N.A. 26.6 93.3 N.A. 93.3 93.3 N.A. 20 0 20 6.6 N.A. 20 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 9 0 9 0 34 42 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 9 9 9 0 9 17 0 17 0 9 % E
% Phe: 0 0 9 0 0 0 0 9 0 9 34 9 0 9 0 % F
% Gly: 0 9 9 0 9 9 50 9 0 9 0 0 0 0 9 % G
% His: 9 0 0 9 42 0 0 0 9 0 0 9 0 9 9 % H
% Ile: 0 0 0 0 0 9 9 0 0 9 9 0 0 9 9 % I
% Lys: 0 0 0 9 0 0 0 9 9 0 9 9 17 9 0 % K
% Leu: 9 9 0 0 0 17 0 17 42 0 0 0 0 9 9 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 0 0 9 0 9 9 0 0 9 0 9 % N
% Pro: 34 9 9 42 17 34 17 0 9 34 9 9 0 9 34 % P
% Gln: 0 9 0 0 17 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 9 42 0 9 9 0 0 0 17 9 0 0 9 0 % R
% Ser: 25 34 9 9 9 9 0 34 0 0 0 59 9 0 9 % S
% Thr: 0 9 0 9 0 0 0 0 9 0 0 9 9 0 0 % T
% Val: 0 9 17 0 0 0 0 9 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _